Issue 50, 2013
From the journal:

Chemical Communications

Locked nucleic acid: tighter is different†

Jonathan K. Watts*a  

* Corresponding authors

a Department of Chemistry and Institute for Life Sciences, University of Southampton, UK
E-mail: j.k.watts@soton.ac.uk
Tel: +44 (0)23 8059 7679

Abstract

This viewpoint briefly reviews the impact of Locked Nucleic Acid (LNA) oligonucleotides, first described in a ChemComm paper in 1998. A number of unique applications in oligonucleotide biotechnology have been made possible by the high binding affinity and specificity of LNA, and these provide the main focus of the viewpoint.

Graphical abstract: Locked nucleic acid: tighter is different

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C3CC40340H
Article type
Viewpoint
Submitted
15 Jan 2013
Accepted
10 Mai 2013
First published
16 Mai 2013

Chem. Commun., 2013,49, 5618-5620

Permissions

Request permissions

Locked nucleic acid: tighter is different

J. K. Watts, Chem. Commun., 2013, 49, 5618 DOI: 10.1039/C3CC40340H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements