Issue 56, 2023

An electrochemical cascade process: synthesis of 3-selenylindoles from 2-alkynylanilines with diselenides

Abstract

Substituted organoselenium compounds are crucial structural motifs in pharmaceutical molecules. Herein, we report a metal, oxidant, and base-free electrochemical approach to access 3-selenylindoles through an oxidative cyclization of 2-alkynylanilines with diselenides. This environmentally friendly approach demonstrates a wide range of substrate scope under mild reaction conditions in an electrochemical undivided cell setup.

Graphical abstract: An electrochemical cascade process: synthesis of 3-selenylindoles from 2-alkynylanilines with diselenides

Supplementary files

Article information

Article type
Communication
Submitted
11 Mai 2023
Accepted
18 Jun 2023
First published
19 Jun 2023

Chem. Commun., 2023,59, 8719-8722

An electrochemical cascade process: synthesis of 3-selenylindoles from 2-alkynylanilines with diselenides

A. B. Dapkekar and G. Satyanarayana, Chem. Commun., 2023, 59, 8719 DOI: 10.1039/D3CC02294C

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