Themed collection Cancer Diagnostics
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Cancer diagnostics
Guest editors Bin Liu and James F. Rusling introduce this Journal of Materials Chemistry B themed issue on cancer diagnostics.
J. Mater. Chem. B, 2018,6, 2507-2509
https://doi.org/10.1039/C8TB90053A
Research progresses on the functional polypeptides in the detection and imaging of breast cancer
Polypeptides as functional groups continue to garner significant interest in the detection and imaging of breast cancer, working as recognition elements, signal sources, building blocks and therapeutic reagents, etc.
J. Mater. Chem. B, 2018,6, 2510-2523
https://doi.org/10.1039/C7TB02541F
A rapid and highly sensitive strain-effect graphene-based bio-sensor for the detection of stroke and cancer bio-markers
A bio-sensor for the detection of cancer biomarkers utilizing the adsorption properties of ruthenium carbonyl on monolayer graphene.
J. Mater. Chem. B, 2018,6, 2536-2540
https://doi.org/10.1039/C8TB00404H
A redox-responsive folate–fluorophore conjugate as a new target-cell-specific imaging probe
Here, we have developed a redox-responsive folate–fluorophore conjugate with a disulfide linker for the target-specific activatable fluorescence imaging of cancers.
J. Mater. Chem. B, 2018,6, 2524-2527
https://doi.org/10.1039/C7TB02180A
Metalla-aromatic loaded magnetic nanoparticles for MRI/photoacoustic imaging-guided cancer phototherapy
In this study, metalla-aromatic agents and a cluster of superparamagnetic iron oxide nanoparticles were loaded inside a micellar carrier and used for MRI/PA imaging-guided PTT/PDT synergistic cancer therapy.
J. Mater. Chem. B, 2018,6, 2528-2535
https://doi.org/10.1039/C7TB02145C
Organic nanoparticles with ultrahigh quantum yield and aggregation-induced emission characteristics for cellular imaging and real-time two-photon lung vasculature imaging
Organic nanoparticles with a high quantum yield of 90% and aggregation-induced emission characteristics were prepared for cellular imaging and real-time two-photon vasculature imaging of the lungs.
J. Mater. Chem. B, 2018,6, 2630-2636
https://doi.org/10.1039/C8TB00386F
An efficient synergistic cancer therapy by integrating cell cycle inhibitor and photosensitizer into polydopamine nanoparticles
A novel polydopamine (PDA) based nanocomposite loaded with cell cycle inhibitor (NOC) and photosensitizer (ZnPc12+) was developed for efficient synergistic cancer therapy.
J. Mater. Chem. B, 2018,6, 2620-2629
https://doi.org/10.1039/C8TB00076J
Imaging and evaluation of sulfane sulfur in acute brain ischemia using a mitochondria-targeted near-infrared fluorescent probe
Imaging and evaluation of sulfane sulfur in acute brain ischemia using a mitochondria-targeted near-infrared fluorescent probe
J. Mater. Chem. B, 2018,6, 2608-2619
https://doi.org/10.1039/C7TB03200E
A novel core–shell structured upconversion nanorod as a multimodal bioimaging and photothermal ablation agent for cancer theranostics
A multifunctional core–shell nanocomposite based on noble metal plasmons coated with upconversion material has emerged as a promising cancer theranostics nanoplatform.
J. Mater. Chem. B, 2018,6, 2597-2607
https://doi.org/10.1039/C7TB02842C
Mannan-based conjugates as a multimodal imaging platform for lymph nodes
We show that mannan-based conjugates possess exceptional features for multimodal imaging because of their biocompatibility, biodegradability and self-targeting properties.
J. Mater. Chem. B, 2018,6, 2584-2596
https://doi.org/10.1039/C7TB02888A
In vivo tumor active cancer targeting and CT-fluorescence dual-modal imaging with nanoprobe based on gold nanorods and InP/ZnS quantum dots
Gold nanorod, InP/ZnS QD and c(RGDfC) based multifunctional nanoprobe for dual-modal imaging of active targeting of tumors in vivo.
J. Mater. Chem. B, 2018,6, 2574-2583
https://doi.org/10.1039/C7TB02643A
Enzyme-instructed self-assembly leads to the activation of optical properties for selective fluorescence detection and photodynamic ablation of cancer cells
An aggregation-induced emission luminogen (AIEgen)-based probe with both fluorescence and photoactivity activatable characteristics is developed for cancer theranostics.
J. Mater. Chem. B, 2018,6, 2566-2573
https://doi.org/10.1039/C7TB02685D
A simple mitochondrial targeting AIEgen for image-guided two-photon excited photodynamic therapy
A simple AIE luminogen, IQ-TPA, with mitochondrial targeting was demonstrated for image-guided two-photon excited photodynamic therapy in cancer cells.
J. Mater. Chem. B, 2018,6, 2557-2565
https://doi.org/10.1039/C7TB02609A
A sequential enzyme-activated and light-triggered pro-prodrug nanosystem for cancer detection and therapy
A sequential enzyme-activated and light-triggered pro-prodrug has been developed for cancer biomarker detection and on-demand therapy.
J. Mater. Chem. B, 2018,6, 2547-2556
https://doi.org/10.1039/C7TB01989K
Near-infrared fluorescent probes for the detection of glutathione and their application in the fluorescence imaging of living cells and tumor-bearing mice
We present two new cyanine-based NIR fluorescent probes for imaging GSH in living cells and tumor-bearing mice.
J. Mater. Chem. B, 2018,6, 2541-2546
https://doi.org/10.1039/C7TB01560G