Themed collection 2024 CRSI Medal Winners Collection

This article explores molecular strategies like homeoviscous adaptation and osmolyte-mediated adaptation that extremophiles use to maintain cell membrane stability under extreme conditions.

Cascade C–C/C–N bond formation of carbonyl ylides with azaoxyallyl cations generated in situ using Rh-catalysis has been accomplished in the presence of a base at room temperature.

For the first time, we present the detailed synthesis, photophysical, electrochemical, host–guest and charge transport properties of spiro[fluorene-9,9′-xanthene] (SFX) and carbazole macrocycle SPS-NR-02.

Extra-terrestrial origins of the simplest α-ketoacids, central to many prebiotic metabolic cycles, have been revealed by simulating the soft impact-induced compression of cometary ices.

This study introduces a novel strategy for developing reversible thermochromic fluorescent films by precisely controlling the nanoscale proximity of boron nitride quantum dots and curcumin molecules within a poly(3-hydroxybutyrate) matrix.

Design, synthesis, photoswitching and computational studies of N-methyl arylazo-3,5-(di-2-pyridyl)pyrazoles and their N-alkyl pyridinium derivatives as probes for pH modulation.

An efficient, straightforward, catalyst- and additive-free synthetic approach for easily accessing keto γ-butyrolactones using readily available β-keto sulfoxonium ylides and acrylic acids has been described.

A highly diastereoselective, one-pot strategy for spirooxindoles bearing dihydrophenanthrenes from readily available isatins and p-quinone methides (p-QMs) has been disclosed.

In situ encapsulation of the 2-(2′-hydroxylphenyl)benzothiazole (HBT) fluorophore into organically modified silica (ORMOSIL) is recognized as a potential approach to increase the photocurrent conversion efficiency.

Pyridyloxy-directed Ir(III)-catalyzed diacylmethylation of protected tyrosines was achieved with alkyl and (hetero)aryl sulfoxonium ylides, furnishing tyrosine-based unnatural amino acids in good yields.

An organophotoredox-catalyzed direct Csp³–H alkylation of 3,4-dihydroquinoxalin-2-ones employing N-(acyloxy)phthalimides to provide corresponding products in good yields is described.

A C(sp³)–C(sp³) cross coupling approach based on an iridium-photocatalytic radical process has been developed for the synthesis of α-alkylated aldehydes from alkyl bromides and trialkyl amines.

Facet control facilitated by primary amines can enhance the optoelectronic characteristics of A₂B^IB′^IIIX₆ perovskite nanocrystals, particularly those with large indirect bandgaps.

Iron-catalyzed stereospecific cascade C–C and C–O bond formation of 2,4-dienals with D–A cyclopropanes has been developed to furnish functionalized cyclopentapyran derivatives.