Issue 17, 2019

Identification of specific pre-analytical quality control markers in plasma and serum samples

Abstract

Blood is a liquid connective tissue with a complex composition that supplies oxygen and nutrients to cells. It is minimally invasive to obtain and can be used in “omics” technologies. Current research regarding blood-based biomarkers has gained considerable attention as a useful tool for diagnostic, therapeutic, and drug development; however, several research groups have reported controversial results despite using the same analytical platform. Such discrepancy can be caused by errors made during the pre-analytical phase. Therefore, quality control of pre-analytical variables is an important factor that could affect the reproducibility and credibility of results. This review discusses the challenge to identify blood quality control markers and describes several molecules that could be potential candidates.

Graphical abstract: Identification of specific pre-analytical quality control markers in plasma and serum samples

Article information

Article type
Critical Review
Submitted
16 яну 2019
Accepted
29 мар 2019
First published
29 мар 2019

Anal. Methods, 2019,11, 2259-2271

Identification of specific pre-analytical quality control markers in plasma and serum samples

L. Ruiz-Godoy, V. Enríquez-Cárcamo, L. Suárez-Roa, M. L. Lopez-Castro, A. Santamaría, M. Orozco-Morales and A. L. Colín-González, Anal. Methods, 2019, 11, 2259 DOI: 10.1039/C9AY00131J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements