Issue 9, 2018
From the journal:

Analyst

Engineering molecularly imprinted polymers (MIPs) for the selective extraction and quantification of the novel psychoactive substance (NPS) methoxphenidine and its regioisomers†

J. W. Lowdon,a   S. M. O. Alkirkit,a   R. E. Mewis, ORCID logo a   D. Fulton,b   C. E. Banks, ORCID logo c   O. B. Sutcliffe ORCID logo ‡*ad  and  M. Peeters ORCID logo ‡*a  

* Corresponding authors

a Manchester Metropolitan University, Faculty of Science and Engineering, School of Science and the Environment, Division of Chemistry and Environmental Science, Chester Street, Manchester M1 5GD, UK
E-mail: o.sutcliffe@mmu.ac.uk, m.peeters@mmu.ac.uk
Tel: +44 (0)161 247 1450

b Newcastle University, School of Chemistry, Bedson Building, Newcastle Upon Tyne, UK

c Manchester Metropolitan University, Faculty of Science and Engineering, School of Healthcare Science, Chester Street, Manchester M1 5GD, UK

d MANchester DRug Analysis and Knowledge Exchange (MANDRAKE), Manchester Metropolitan University, Faculty of Science and Engineering, Chester Street, Manchester M1 5GD, UK

Abstract

In this communication, we present the first developed Molecularly Imprinted Polymers (MIPs) for the specific detection of a New Psychoactive Substance (NPS); namely, methoxphenidine (MXP) and its regioisomers. Selectivity of the MIP towards MXP is studied by analysing mixtures and an acquired street sample with High Performance Liquid Chromatography coupled to UV detection. The study demonstrates that the engineered polymers selectively extract MXP from heterogeneous samples, which makes for a very powerful diagnostic tool that can detect traces of MXP in complicated NPS samples.

Graphical abstract: Engineering molecularly imprinted polymers (MIPs) for the selective extraction and quantification of the novel psychoactive substance (NPS) methoxphenidine and its regioisomers

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8AN00131F
Article type
Communication
Submitted
23 яну 2018
Accepted
11 апр 2018
First published
12 апр 2018
This article is Open Access
Creative Commons BY-NC license

Analyst, 2018,143, 2002-2007

Permissions

Request permissions

Engineering molecularly imprinted polymers (MIPs) for the selective extraction and quantification of the novel psychoactive substance (NPS) methoxphenidine and its regioisomers

J. W. Lowdon, S. M. O. Alkirkit, R. E. Mewis, D. Fulton, C. E. Banks, O. B. Sutcliffe and M. Peeters, Analyst, 2018, 143, 2002 DOI: 10.1039/C8AN00131F

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements