Issue 6, 2010
From the journal:

Chemical Communications

Diastereoselective and enantioselective Mukaiyama aldol reactions of α-ketoesters using hydrogen bond catalysis†‡

Vijaya Bhasker Gondi,a   Koji Hagiharaa  and  Viresh H. Rawal*a  

* Corresponding authors

a Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA
E-mail: vrawal@uchicago.edu
Fax: +1-773-702-0805
Tel: +1-773-702-2194

Abstract

Hydrogen bond catalyzed Mukaiyama aldol reactions of α-ketoesters proceed in high diastereo- and enantioselectivities, giving products possessing two chiral centers, of which one is a tertiary alcohol.

Graphical abstract: Diastereoselective and enantioselective Mukaiyama aldol reactions of α-ketoesters using hydrogen bond catalysis

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B919929B
Article type
Communication
Submitted
24 сеп 2009
Accepted
17 дек 2009
First published
11 яну 2010

Chem. Commun., 2010,46, 904-906

Permissions

Request permissions

Diastereoselective and enantioselective Mukaiyama aldol reactions of α-ketoesters using hydrogen bond catalysis

V. B. Gondi, K. Hagihara and V. H. Rawal, Chem. Commun., 2010, 46, 904 DOI: 10.1039/B919929B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements