Designing biomimetic catalytic systems for CO2 reduction to formate using NAD(P)H
This review article focuses on current achievements and identifies future research directions by designing biomimetic catalytic systems for CO2 reduction to formate using NAD(P)H.
Review Article
Metal–coumarin derivatives as promising photosensitizers: unlocking their cancer phototherapy potential
Metal–coumarin photosensitizers enhance ROS generation and phototoxicity, offering promising solutions for cancer phototherapy.
Immunogenic cell death-inducing Rh(I) and Ir(I) complexes with bis(imino)acenaphthene-derived ligands: insights into the role of the metal center and the ligands
The Rh(I) complex 3a with the 1,2-bis[(2,6-diisopropylphenyl)imino]acenaphthene (dpp-bian) ligand induces type I immunogenic cell death (ICD), whereas the analogous Ir(I) complex does not, revealing metal-specific immunogenicity.
Research Article
The impact of albumin conjugation on the cytotoxic properties of cisplatin, oxaliplatin and auranofin in cancer cells
HSA bioconjugates with cisplatin, oxaliplatin, and auranofin showed distinct cytotoxicity profiles, highlighting Pt vs. Au differences in cancer cells.
Research Article
Design of porous self-assembled homoleptic and heteroleptic Pd2+ cages incorporating silicon-based fluoride acceptors: the way towards nuclear imaging applications
Homoleptic and heteroleptic Pd2+ cages incorporating targeting peptides where synthesized, characterized, and successfully 18F-radiolabeled. This work moves forward the field of self-assembled coordination complexes for nuclear imaging applications.
An effective and selective non-heme iron-catalyzed hydroxylation of alkane C–H bonds
Mononuclear non-heme iron complexes 1 and 2 demonstrate excellent selectivity in the oxidation of alkanes under ambient conditions. HR-MS combined with EPR analysis identified the involvement of the FeIII-peroxo intermediate.
pH-Modulated activation of a pendant amine leading to rapid electrocatalytic H2 production by a molecular copper complex in acidic water
A uniquely positioned pendant amine-mediated molecular Cu-complex-driven rapid electrocatalytic H2 production reaction in water.
Research Article
Selective aromatic halogenation by a manganese compound I model: a mimic of chloroperoxidase
A high-valent manganese compound I complex, Mn Cpd I, displays a high reactivity in aromatic halogenation. This study provides valuable insights into understanding of the reaction mechanism of aromatic halogenation by Mn-porphyrin intermediates.
A platinated prodrug leveraging PROTAC technology for targeted protein degradation and enhanced antitumor efficacy
PROTAC–Pt(IV) represents a new class of dual-action Pt(IV) prodrugs integrating platinum drugs with PROTAC-mediated protein degradation, exhibiting superior antitumor efficacy compared to conventional Pt(IV) prodrug and PROTAC alone in vivo.
Photoinduced NO release of [Fe2(μ-SL)2(NO)4] complexes and their protein adducts: insights from structure, cytotoxicity, and photodynamic studies
Photoinduced NO release and cytotoxicity of four nitrosyl Fe–S complexes modified with different thiolate bridging ligands and their ferritin complex adducts were investigated.
Novel zinc(II) phthalocyanine nanoparticles as a diagnosis–treatment nanoprobe for photoacoustic-imaging-guided synergistic photothermal/photodynamic-enhanced cancer therapy
In this work, novel zinc(II) phthalocyanine nanoparticles (ZnPcNPs) have been developed and verified to be a promising PTT/PDT agent with a high photoconversion efficiency of 30.01% under 660 nm NIR-I laser exposure.
Synthesis and bio-evaluation of aminoferrocene-based anticancer prodrugs as potent ferroptosis inducers
Novel ROS-responsive N-alkylaminoferrocene (NAAF)-appended GPX4 inhibitors have been designed and prepared as potent ferroptosis-inducing prodrugs.
About this collection
This special collection of Inorganic Chemistry Frontiers is dedicated to the 11th Asian Biological Inorganic Chemistry Conference (AsBIC11), which was held in Guilin, China from December 1-6, 2024.