Issue 13, 2017

Recent progress in surface-enhanced Raman spectroscopy for biological and biomedical applications: from cells to clinics

Abstract

The application of surface-enhanced Raman spectroscopy (SERS) in biological and biomedical detection schemes is feasible due to its excellent molecular specificity and high sensitivity as well as the capability of SERS to be performed in complex biological compositions. SERS-based investigation of cells, which are the basic structure and functional unit of organisms, represents the starting point of this review. It is demonstrated that SERS provides a deep understanding of living cells as well as their microenvironment which is needed to assess the development of diseases. The clinical relevance of SERS is proved by its application for the detection of cancer cells and tumour margins under in vivo conditions and examples for theranostic approaches are discussed. This review article provides a comprehensive overview of the recent progress within the last 3 years.

Graphical abstract: Recent progress in surface-enhanced Raman spectroscopy for biological and biomedical applications: from cells to clinics

Article information

Article type
Review Article
Submitted
07 mar 2017
First published
22 iyn 2017

Chem. Soc. Rev., 2017,46, 3945-3961

Recent progress in surface-enhanced Raman spectroscopy for biological and biomedical applications: from cells to clinics

D. Cialla-May, X.-S. Zheng, K. Weber and J. Popp, Chem. Soc. Rev., 2017, 46, 3945 DOI: 10.1039/C7CS00172J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements