Issue 66, 2020

Copper-catalysed ortho-selective C–H bond functionalization of phenols and naphthols with α-aryl-α-diazoesters

Abstract

Herein, we reported the first copper-catalyzed highly efficient C(sp2)–H functionalization of unprotected naphthols and phenols with α-aryl-α-diazoesters. In this transformation, CuCl2 efficiently promoted the highly chemo- and site-selective C–H bond functionalization under mild conditions, furnishing diverse phenol derivatives in moderate to excellent yields from readily available starting materials.

Graphical abstract: Copper-catalysed ortho-selective C–H bond functionalization of phenols and naphthols with α-aryl-α-diazoesters

Supplementary files

Article information

Article type
Communication
Submitted
30 iyn 2020
Accepted
09 iyl 2020
First published
09 iyl 2020

Chem. Commun., 2020,56, 9485-9488

Copper-catalysed ortho-selective C–H bond functionalization of phenols and naphthols with α-aryl-α-diazoesters

B. Ma, Z. Tang, J. Zhang and L. Liu, Chem. Commun., 2020, 56, 9485 DOI: 10.1039/D0CC04495D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements