Issue 31, 2015

The role of tissue engineering in cellular therapies for myocardial infarction: a review

Abstract

Current medical treatments of myocardial infarction (MI) face a serious shortcoming in that they cannot reverse the detrimental effects of ischemia induced necrosis. In searching for novel solutions to this medical problem, great focus has been placed on cardiac tissue engineering. Recently much progress has been made using cellular approaches, with multiple studies undergoing clinical trials. Non-cellular approaches for the construction of engineered cardiac tissue have also achieved some major breakthroughs, although drawbacks remain. In this review article, an update on the progress of a non-cellular approach is discussed with major focus on the two main scaffold types: implantable cardiac patches and injectable cardiac hydrogels. The design properties, cell sources, and material properties are briefly described.

Graphical abstract: The role of tissue engineering in cellular therapies for myocardial infarction: a review

Supplementary files

Article information

Article type
Review Article
Submitted
21 apr 2015
Accepted
04 iyn 2015
First published
10 iyn 2015

J. Mater. Chem. B, 2015,3, 6401-6410

Author version available

The role of tissue engineering in cellular therapies for myocardial infarction: a review

Y. (. Wu and J. Yu, J. Mater. Chem. B, 2015, 3, 6401 DOI: 10.1039/C5TB00739A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements