Issue 12, 2006

Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules

Abstract

Significant progress has been made in the direct arylation of simple arenes. A number of catalyst systems have been developed which enable the intramolecular direct arylation of aryl chlorides, bromides and iodides in high yield as well as conditions capable of achieving intermolecular direct arylation with simple arenes. This account describes recent progress by our group and others in the development of these reactions.

Graphical abstract: Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules

Article information

Article type
Feature Article
Submitted
29 رمضان 1426
Accepted
20 ذو القعدة 1426
First published
30 ذو الحجة 1426

Chem. Commun., 2006, 1253-1264

Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules

L. Campeau and K. Fagnou, Chem. Commun., 2006, 1253 DOI: 10.1039/B515481M

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