Issue 25, 2015

Photoelectric artefact from optogenetics and imaging on microelectrodes and bioelectronics: new challenges and opportunities

Abstract

Bioelectronics, electronic technologies that interface with biological systems, are experiencing rapid growth in terms of technology development and applications, especially in neuroscience and neuroprosthetic research. The parallel growth with optogenetics and in vivo multi-photon microscopy has also begun to generate great enthusiasm for simultaneous applications with bioelectronic technologies. However, emerging research showing artefact contaminated data highlight the need for understanding the fundamental physical principles that critically impact experimental results and complicate their interpretation. This review covers four major topics: (1) material dependent properties of the photoelectric effect (conductor, semiconductor, organic, photoelectric work function (band gap)); (2) optic dependent properties of the photoelectric effect (single photon, multiphoton, entangled biphoton, intensity, wavelength, coherence); (3) strategies and limitations for avoiding/minimizing photoelectric effects; and (4) advantages of and applications for light-based bioelectronics (photo-bioelectronics).

Graphical abstract: Photoelectric artefact from optogenetics and imaging on microelectrodes and bioelectronics: new challenges and opportunities

Article information

Article type
Review Article
Submitted
16 ጃንዩ 2015
Accepted
07 ኤፕሪ 2015
First published
13 ኤፕሪ 2015

J. Mater. Chem. B, 2015,3, 4965-4978

Author version available

Photoelectric artefact from optogenetics and imaging on microelectrodes and bioelectronics: new challenges and opportunities

T. D. Y. Kozai and A. L. Vazquez, J. Mater. Chem. B, 2015, 3, 4965 DOI: 10.1039/C5TB00108K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements