Issue 25, 2015

Organic bioelectronics in infection


Organic bioelectronics is a rapidly growing field of both academic and industrial interest. Specific attributes make this class of materials particularly interesting for biomedical and medical applications, and a whole new class of biologically compatible devices is being created owing to structural and functional similarities to biological systems. In parallel, modern advances in biomedical research call for dynamically controllable systems. In infection biology, a progressing bacterial infection can be studied dynamically, at much higher resolution and on a smaller spatial scale than ever before, and it is now understood that minute changes in the tissue microenvironment play pivotal roles in the outcome of infections. This review merges the fields of infection biology and organic bioelectronics, describing the ability of conducting polymer devices to sense, modify, and interact with the infected tissue microenvironment. Though the primary focus is from the perspective of bacterial infections, general examples from cell biology and regenerative medicine are included where relevant. Spatially and temporally controlled biomimetic in vitro systems will greatly aid our molecular understanding of the infection process, thereby providing exciting opportunities for organic bioelectronics in future diagnosis and treatment of infectious diseases.

Graphical abstract: Organic bioelectronics in infection

Article information

Article type
Review Article
26 Feb 2015
30 Apr 2015
First published
01 May 2015
This article is Open Access
Creative Commons BY-NC license

J. Mater. Chem. B, 2015,3, 4979-4992

Author version available

Organic bioelectronics in infection

S. Löffler, B. Libberton and A. Richter-Dahlfors, J. Mater. Chem. B, 2015, 3, 4979 DOI: 10.1039/C5TB00382B

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity