Issue 41, 2024

A flexible electrochemical sensor based on Fe-doped polydopamine derived carbon for simultaneous detection of dopamine and uric acid

Abstract

A free-standing electrode based on carbon cloth-supported Fe-doped polydopamine-derived carbon (Fe/PDA-C/CC) was developed for the simultaneous detection of dopamine (DA) and uric acid (UA). First, dopamine was self-polymerized on the surface of the carbon cloth to obtain polydopamine coatings. Subsequently, Fe3+ was introduced through the formation of a coordinate bond with the hydroxyl functional group in the polydopamine layer. After calcination, a flexible and free-standing electrode was obtained. The sensing performance and mechanism of the Fe/PDA-C/CC sensor was investigated and is discussed in detail herein. Experimental results demonstrated that Fe/PDA-C/CC could simultaneously detect DA and UA with a wide detection range of 0.5–300 μM and 0.5–400 μM with low detection limits of 0.041 μM and 0.012 μM, respectively. Meanwhile, Fe/PDA-C/CC possessed excellent anti-interference performance, repeatability, stability, and accuracy in real samples. Overall, this study provides a facile and effective approach for simultaneous detection of UA and DA.

Graphical abstract: A flexible electrochemical sensor based on Fe-doped polydopamine derived carbon for simultaneous detection of dopamine and uric acid

Supplementary files

Article information

Article type
Paper
Submitted
26 Cax 2024
Accepted
02 Way 2024
First published
03 Way 2024

Anal. Methods, 2024,16, 6974-6987

A flexible electrochemical sensor based on Fe-doped polydopamine derived carbon for simultaneous detection of dopamine and uric acid

X. Wang, W. Wang, M. Gao, M. Fu, L. Ma and W. Chen, Anal. Methods, 2024, 16, 6974 DOI: 10.1039/D4AY00980K

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