Photochemical degradation of antibiotics: real-time investigation by aerodynamic thermal breakup droplet ionization mass spectrometry

Abstract

A method is proposed for studying photochemical reactions in solution in real time using aerodynamic/thermal breakup droplet ionization mass spectrometry. Capabilities of the method were demonstrated by analyses of photodegradation processes of three antibiotics (thiamphenicol, ciprofloxacin, and ofloxacin) by means of aqueous solutions. The method rapidly provided information about photochemical changes for understanding the photochemical processes.

Graphical abstract: Photochemical degradation of antibiotics: real-time investigation by aerodynamic thermal breakup droplet ionization mass spectrometry

Supplementary files

Article information

Article type
Paper
Submitted
05 Aug 2024
Accepted
10 Sep 2024
First published
11 Sep 2024

Anal. Methods, 2024, Advance Article

Photochemical degradation of antibiotics: real-time investigation by aerodynamic thermal breakup droplet ionization mass spectrometry

D. G. Sheven and V. V. Pervukhin, Anal. Methods, 2024, Advance Article , DOI: 10.1039/D4AY01459F

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