RSC Advances  

The global community is faced with numerous health concerns such as cancer, cardiovascular and neurological diseases, diabetes, joint pain, osteoporosis, among others.

Seven new oleanane saponins were discovered from Dendrobium officinale. These saponins containing 29-noroleana-12,20(30)-dien-28-oic acid framework, caffeoyl, and coumaroyl moieties potentially inhibited α-glucosidase and α-amylase activities.

Analytical technique for monitoring skin-emitted metabolites to diagnose diseases.

Aim to provide practical clinical guidance for the treatment of implants in diabetic patients, this study investigated the corrosion mechanism of bionic coatings containing different Ca/P ratios in diabetic environments.

The diminishing supply of fossil fuels, their detrimental environmental effects, and the challenges associated with the disposal of agro-waste necessitated the development of renewable and sustainable alternative energy sources.

Metabolomic profiling of Caroxylon volkensii by LC-QTOF-MS/MS and investigating the components responsible for its antibacterial and anti-biofilm activities using molecular docking.

Alzheimer has many crucial factors that should be considered in order to get better results from clinical trials. Benzimidazole and its isosteres represent significant scaffolds for designing potential multi-target anti-alzheimer molecules.

Carpesabrolide A is a fumaric acid–guaiane sesquiterpenoid hybrid isolated from the medicinal plant Carpesium abrotanoides. It significantly inhibited NO production with an IC₅₀ value of 2.7 μM.

Emulsified water droplets and wax crystals can show different collision and aggregation behaviors in stages under dynamic cooling conditions.

Piper nigrum L. (black and white peppercorn) is one of the most common culinary spices used worldwide.

A user-friendly LC-MS data-independent acquisition-based strategy using open software for access to the flavonoid content of complex mixtures.

Preparation of EGCG–Zn–CS using Microwave Irradiation method with excellent biological activity.

Vitamins are crucial micronutrients found in limited quantities in food, living organisms, and soil.

Monoamine oxidases (MAOs) inhibitors could decrease reactive oxygen species (ROS) generation, enhance mono-aminergic neural transmission, and have major therapeutic benefits for the treatment of Alzheimer's disease (AD).

Atlantic cod (Gadus morhua) is a good source for producing umami peptides, and 2 novel umami pentapeptides were first identified from which. The physicochemical properties, cytotoxicity, and taste mechanisms of 2 umami peptides were also explored.

The Sn–I metabolite decreases the contractile response to KCl or phenylephrine (PE) mainly by blocking Ca²⁺ entry through voltage-gated Ca²⁺ channel (VGCC).

The new classification of APAP combinations (prodrugs, codrugs, and hybrids) was proposed. It makes a better understanding of the SAR studies for new pain relievers research and the design development for the analgesic APAP-based compounds.

New pyrimidine-based carbocylic nucleoside derivatives with C-4 substitution for inhibiting α-glucosidase as a means of alleviating the effects of diabetes mellitus (DM) and microbial infections.

Sulfobutylether β-cyclodextrin can significantly improve the antioxidant and antibacterial activities of quercetin through the formation of an inclusion complex, and their interactions have been elucidated.

Research into innovative food safety technologies has led to the development of smart packaging with embedded chemical sensors that can monitor food quality throughout the supply chain.

Various nanoformulations of ZnO and Stixis scandens leaf extract were successfully synthesized. The A1T nanoformulation, containing only 7.6% extract, showed an equivalent anti-PEDV activity with the extract.

4-Nonylphenol, an emerging endocrine disruptor, raises health concerns. Radiolabeling and in vivo tracing of 4NP reveal significant tissue accumulation, emphasizing intricate distribution and potential long-term effects for risk assessments.

Silica-coated lanthanide-doped upconverting nanoparticles (UCNPs) are internalized by mammalian cells. The bipyramidal UCNPs are non-toxic and elicit minor stress responses in a cell type-dependent fashion.

A novel colorimetric affordable test strip was developed for the colorimetric and naked-eye detection of two biogenic amines.

Anti-wear performance is a crucial quality of lubricants, and it is important to conduct research into the structure–activity relationship of anti-wear additives in bio-based lubricants.