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Themed collection Imaging Metals in Biology

8 articles
Editorial

Imaging metals in biology: pictures of metals in health and disease

Guest editors Dominic Hare, Elizabeth New and Gawain McColl introduce this themed issue of Metallomics on the topic of Imaging Metals in Biology.

Graphical abstract: Imaging metals in biology: pictures of metals in health and disease
From the themed collection: Imaging Metals in Biology
Minireview

A ubiquitous metal, difficult to track: towards an understanding of the regulation of titanium(IV) in humans

Molecular mechanisms in the body regulate the cytotoxic properties of titanium(IV) such that Ti(IV) could be bioavailable for cellular functions.

Graphical abstract: A ubiquitous metal, difficult to track: towards an understanding of the regulation of titanium(iv) in humans
From the themed collection: Recent HOT articles
Tutorial Review

Application of imaging mass spectrometry approaches to facilitate metal-based anticancer drug research

Mass spectrometry imaging is being increasingly used in metal-based anticancer drug development to study elemental and/or molecular drug distributions in different biological systems.

Graphical abstract: Application of imaging mass spectrometry approaches to facilitate metal-based anticancer drug research
From the themed collection: Recent HOT articles
Critical Review

Imaging metals in Caenorhabditis elegans

Possible analytical imaging approaches and their advantages and disadvantages for the study of metal (M) distribution in C. elegans.

Graphical abstract: Imaging metals in Caenorhabditis elegans
From the themed collection: Imaging Metals in Biology
Open Access Paper

Whole-brain metallomic analysis of the common marmoset (Callithrix jacchus)

This work represents the first whole-brain LA-ICP-MS metallomic map of a non-human primate species.

Graphical abstract: Whole-brain metallomic analysis of the common marmoset (Callithrix jacchus)
From the themed collection: Imaging Metals in Biology
Open Access Paper

Age modulates the injury-induced metallomic profile in the brain

Iron, copper and zinc may contribute to the neuronal pathologies that occurs following brain injury. We show here that there is a unique profile of metal alterations in the aged mouse brain following trauma which is distinct from that seen in younger animals.

Graphical abstract: Age modulates the injury-induced metallomic profile in the brain
From the themed collection: Zinc in the Biosciences
Open Access Paper

Detection of Zn2+ release in nitric oxide treated cells and proteome: dependence on fluorescent sensor and proteomic sulfhydryl groups

Fluorescence detection of Zn2+ mobilized from cell proteome by nitric oxide (NO) is sensor dependent.

Graphical abstract: Detection of Zn2+ release in nitric oxide treated cells and proteome: dependence on fluorescent sensor and proteomic sulfhydryl groups
From the themed collection: Zinc in the Biosciences
Paper

Intracellular distribution and stability of a luminescent rhenium(I) tricarbonyl tetrazolato complex using epifluorescence microscopy in conjunction with X-ray fluorescence imaging

The cellular distribution of a Re(I) complex has been imaged using X-ray fluorescence and correlated to its inherent luminescence.

Graphical abstract: Intracellular distribution and stability of a luminescent rhenium(i) tricarbonyl tetrazolato complex using epifluorescence microscopy in conjunction with X-ray fluorescence imaging
From the themed collection: Imaging Metals in Biology
8 articles

About this collection

This themed collection of papers reflect the current state-of-play in metal imaging by presenting applications that provide new understanding of how metals regulate normal biochemistry and how this critical balance is lost during disease. Guest Edited by Dominic Hare, Gawain McColl and Elizabeth New, new articles will be added to this collection as they are published.

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