Issue 5, 2017
From the journal:

Organic & Biomolecular Chemistry

Kinetic enantioselectivity of a protonated bis(diamido)-bridged basket resorcin[4]arene towards alanine peptides†

C. Fraschetti,a   M. Montagna,a   M. E. Crestoni,a   A. Calcaterra,a   F. Aiello,b   L. Santia  and  A. Filippi*a  

* Corresponding authors

a Dipartimento di Chimica e Tecnologie del Farmaco, “Sapienza” Università di Roma, P.le A. Moro 5, 00185 Roma, Italy
E-mail: antonello.filippi@uniroma1.it
Fax: +39-06-49913602
Tel: +39-06-49913923

b Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Pisa, Italy

Abstract

Efficient enantiodiscrimination of some alanine-containing di- and tri-peptides by using chiral protonated bis(diamido)-bridged basket resorcin[4]arenes depends on several factors, including the basicity of the amino acid residues at the C- and N-termini of the peptide.

Graphical abstract: Kinetic enantioselectivity of a protonated bis(diamido)-bridged basket resorcin[4]arene towards alanine peptides

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Article information

DOI
https://doi.org/10.1039/C6OB02734B
Article type
Paper
Submitted
14 Dec 2016
Accepted
23 Dec 2016
First published
23 Dec 2016

Org. Biomol. Chem., 2017,15, 1183-1189

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Kinetic enantioselectivity of a protonated bis(diamido)-bridged basket resorcin[4]arene towards alanine peptides

C. Fraschetti, M. Montagna, M. E. Crestoni, A. Calcaterra, F. Aiello, L. Santi and A. Filippi, Org. Biomol. Chem., 2017, 15, 1183 DOI: 10.1039/C6OB02734B

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