Issue 29, 2013
From the journal:

Chemical Communications

Sterically bulky caging for light-inducible protein activation†

Satoshi Takamori,a   Satoshi Yamaguchi,*a   Noriyuki Ohashia  and  Teruyuki Nagamune*ab  

* Corresponding authors

a Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan

b Department of Bioengineering, School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan
E-mail: yamaguchi@bio.t.u-tokyo.ac.jp, nagamune@bioeng.t.u-tokyo.ac.jp
Fax: +81 (0)3 5841 8657
Tel: +81 (0)3 5841 7328

Abstract

A method for caging a target protein with steric regulator molecules was developed to enable simple, strict, light-induced control of protein activity.

Graphical abstract: Sterically bulky caging for light-inducible protein activation

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Article information

DOI
https://doi.org/10.1039/C3CC38026B
Article type
Communication
Submitted
06 Nov 2012
Accepted
25 Feb 2013
First published
25 Feb 2013

Chem. Commun., 2013,49, 3013-3015

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Sterically bulky caging for light-inducible protein activation

S. Takamori, S. Yamaguchi, N. Ohashi and T. Nagamune, Chem. Commun., 2013, 49, 3013 DOI: 10.1039/C3CC38026B

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