Issue 29, 2013
From the journal:

Chemical Communications

In vivo imaging using polymeric nanoparticles stained with near-infrared chemiluminescent and fluorescent squarainecatenane endoperoxide†

Jung-Jae Lee,a   Alexander G. White,a   Douglas R. Ricea  and  Bradley D. Smith*a  

* Corresponding authors

a Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA
E-mail: smith.115@nd.edu
Fax: +1 574 6316652
Tel: +1 574 6318632

Abstract

Polystyrene nanoparticles stained with squaraine catenane endoperoxide exhibit remarkably high chemiluminescence and enable optical imaging of biodistribution in living mice. Whole-body chemiluminescence imaging was much more effective than fluorescence at identifying lung accumulation of the nanoparticles.

Graphical abstract: In vivo imaging using polymeric nanoparticles stained with near-infrared chemiluminescent and fluorescent squaraine catenane endoperoxide

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Article information

DOI
https://doi.org/10.1039/C3CC40630J
Article type
Communication
Submitted
24 Jan 2013
Accepted
26 Feb 2013
First published
28 Feb 2013

Chem. Commun., 2013,49, 3016-3018

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In vivo imaging using polymeric nanoparticles stained with near-infrared chemiluminescent and fluorescent squaraine catenane endoperoxide

J. Lee, A. G. White, D. R. Rice and B. D. Smith, Chem. Commun., 2013, 49, 3016 DOI: 10.1039/C3CC40630J

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