Issue 8, 2012
From the journal:

Green Chemistry

One-pot chemoenzymatic synthesis of aldoximes from primary alcohols in water

Paolo Zambelli,a   Andrea Pinto,b   Diego Romano,a   Elena Crotti,a   Paola Conti,b   Lucia Tamborini,b   Raffaella Villac  and  Francesco Molinaria  

a Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy
E-mail: francesco.molinari@unimi.it
Fax: +39 0250319191
Tel: +39 0250319148

b Department of Pharmaceutical Sciences, University of Milan, Milan, Italy

c School of Applied Sciences, Cranfield University, Bedford, UK

Abstract

A new synthetic method for the one-pot preparation of aldoximes in water was developed; the method is based on the combination of the enzymatic oxidation of primary alcohols to aldehydes using different acetic acid bacteria and in situ condensation of the aldehydes with hydroxylamine.

Graphical abstract: One-pot chemoenzymatic synthesis of aldoximes from primary alcohols in water

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Article information

DOI
https://doi.org/10.1039/C2GC35764J
Article type
Communication
Submitted
18 May 2012
Accepted
18 Jun 2012
First published
19 Jun 2012

Green Chem., 2012,14, 2158-2161

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One-pot chemoenzymatic synthesis of aldoximes from primary alcohols in water

P. Zambelli, A. Pinto, D. Romano, E. Crotti, P. Conti, L. Tamborini, R. Villa and F. Molinari, Green Chem., 2012, 14, 2158 DOI: 10.1039/C2GC35764J

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