Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 5, 2015
Previous Article Next Article

The marine actinomycete genus Salinispora: a model organism for secondary metabolite discovery

Author affiliations

Abstract

Covering: 2001 to 2014

This review covers the initial discovery of the marine actinomycete genus Salinispora through its development as a model for natural product research. A focus is placed on the novel chemical structures reported with reference to their biological activities and the synthetic and biosynthetic studies they have inspired. The time line of discoveries progresses from more traditional bioassay-guided approaches through the application of genome mining and genetic engineering techniques that target the products of specific biosynthetic gene clusters. This overview exemplifies the extraordinary biosynthetic diversity that can emanate from a narrowly defined genus and supports future efforts to explore marine taxa in the search for novel natural products.

Graphical abstract: The marine actinomycete genus Salinispora: a model organism for secondary metabolite discovery

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 30 Dec 2014 and first published on 02 Mar 2015


Article type: Review Article
DOI: 10.1039/C4NP00167B
Citation: Nat. Prod. Rep., 2015,32, 738-751
  •   Request permissions

    The marine actinomycete genus Salinispora: a model organism for secondary metabolite discovery

    P. R. Jensen, B. S. Moore and W. Fenical, Nat. Prod. Rep., 2015, 32, 738
    DOI: 10.1039/C4NP00167B

Search articles by author