Issue 66, 2022

Photoredox synthesis of 6- and 7-membered ring scaffolds via N-centered radicals

Abstract

N-Containing heterocycles are important scaffolds due to their ubiquitous presence in bioactive compounds. Their synthesis has been considered as an important research field. In this work we report the access to 6- and 7-membered rings via a photoinduced strategy. To our knowledge, this work represents the first exemple of photo-induced 7-endo-trig cyclization with N-centered radicals.

Graphical abstract: Photoredox synthesis of 6- and 7-membered ring scaffolds via N-centered radicals

Supplementary files

Article information

Article type
Communication
Submitted
16 May 2022
Accepted
13 Jul 2022
First published
13 Jul 2022
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2022,58, 9206-9209

Photoredox synthesis of 6- and 7-membered ring scaffolds via N-centered radicals

W. Boiledieu, M. De Abreu, C. Cuyamendous, D. Lamaa, P. Belmont and E. Brachet, Chem. Commun., 2022, 58, 9206 DOI: 10.1039/D2CC02780A

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