Jump to main content
Jump to site search

Issue 8, 2018
Previous Article Next Article

Synthesis of trans-disubstituted-2,3-dihydrobenzofurans by a formal [4 + 1] annulation between para-quinone methides and sulfonium salts

Author affiliations

Abstract

An efficient protocol for the synthesis of trans-disubstituted-2,3-dihydrobenzofurans through [4 + 1] annulation of para-quinone methides with sulfonium salts has been developed. Under very mild conditions this unprecedented reaction occurs in good to excellent yields (up to 99%), offering a straightforward access to a variety of 2,3-dihydrobenzofurans.

Graphical abstract: Synthesis of trans-disubstituted-2,3-dihydrobenzofurans by a formal [4 + 1] annulation between para-quinone methides and sulfonium salts

Back to tab navigation

Supplementary files

Publication details

The article was received on 04 Jan 2018, accepted on 26 Feb 2018 and first published on 27 Feb 2018


Article type: Research Article
DOI: 10.1039/C8QO00008E
Citation: Org. Chem. Front., 2018,5, 1348-1351
  •   Request permissions

    Synthesis of trans-disubstituted-2,3-dihydrobenzofurans by a formal [4 + 1] annulation between para-quinone methides and sulfonium salts

    Y. Zhi, K. Zhao, C. von Essen, K. Rissanen and D. Enders, Org. Chem. Front., 2018, 5, 1348
    DOI: 10.1039/C8QO00008E

Search articles by author

Spotlight

Advertisements