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Issue 61, 2017
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Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles

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Abstract

A Zn(OTf)2-promoted cyclization reaction of tosylhydrazones with 2-(dimethylamino)malononitrile has been successfully developed providing an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles.

Graphical abstract: Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles

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Publication details

The article was received on 14 Jun 2017, accepted on 05 Jul 2017 and first published on 06 Jul 2017


Article type: Communication
DOI: 10.1039/C7CC04610C
Citation: Chem. Commun., 2017,53, 8545-8548
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    Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles

    B. Zhang, L. Lei, S. Liu, X. Mou, W. Liu, S. Wang, J. Wang, W. Bao and K. Zhang, Chem. Commun., 2017, 53, 8545
    DOI: 10.1039/C7CC04610C

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