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Controllable Porosity Conversion of Metal-Organic Frameworks Composed of Natural Ingredients for Drug Delivery

Abstract

Two extremely rare beta-cyclodextrin (beta-CD) supported metal-organic frameworks (MOFs), CD-MOF-1 and CD-MOF-2, were induced to crystalize for the first time through a template-induced approach. A large number of control experiments indicated that the selected template has a significant implication on the crystallinity and porosity of resulting CD-MOF. The targeted CD-MOFs were employed to perform controlled drug delivery and cytotoxicity assays that confirmed their favourable biological potential of being as drug carriers.

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Publication details

The article was received on 11 May 2017, accepted on 19 Jun 2017 and first published on 19 Jun 2017


Article type: Communication
DOI: 10.1039/C7CC03673F
Citation: Chem. Commun., 2017, Accepted Manuscript
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    Controllable Porosity Conversion of Metal-Organic Frameworks Composed of Natural Ingredients for Drug Delivery

    Y. Lan, J. Liu, T. Bao, X. Yang, P. Zhu, L. Wu, J. Sha, L. Zhang, L. Dong and X. Cao, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC03673F

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