A host–guest system based on collagen-like triple-helix hybridization†
Abstract
A strategy inspired by tweezer receptors has been employed to develop a new host–guest system. The hybridization into a collagen-like triple helix is the driving force for the recognition that occurs with high affinity and selectivity. Several systems have been screened to find the best host–guest pair and this strategy may be implemented for tag fused protein recognition.