Issue 37, 2016
From the journal:

Organic & Biomolecular Chemistry

Double heteroannulation of S,N-acetals: a facile access to quinolone derivatives†

Manojkumar Janni,a   Sahil Aroraa  and  S. Peruncheralathan*a  

* Corresponding authors

a School of Chemical Sciences, National Institute of Science Education and Research (NISER), Bhimpur-Padanpur (PO), Jatni (via), Khurda – 752050, Odisha, India
E-mail: peru@niser.ac.in
Fax: +91-674-2494004
Tel: +91-674-2494173

Abstract

A rapid construction of quinolone fused heterocycles from single S,N-acetal precursors via double heteroannulation is described. The base, radical and metal-mediated reactions can control the C–N, C–S and C–O bond formations of the S,N-acetal with high chemoselectivity.

Graphical abstract: Double heteroannulation of S,N-acetals: a facile access to quinolone derivatives

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Article information

DOI
https://doi.org/10.1039/C6OB01568A
Article type
Paper
Submitted
22 Jul 2016
Accepted
19 Aug 2016
First published
19 Aug 2016

Org. Biomol. Chem., 2016,14, 8781-8788

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Double heteroannulation of S,N-acetals: a facile access to quinolone derivatives

M. Janni, S. Arora and S. Peruncheralathan, Org. Biomol. Chem., 2016, 14, 8781 DOI: 10.1039/C6OB01568A

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