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Issue 47, 2015
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On scattered waves and lipid domains: detecting membrane rafts with X-rays and neutrons

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Abstract

In order to understand the biological role of lipids in cell membranes, it is necessary to determine the mesoscopic structure of well-defined model membrane systems. Neutron and X-ray scattering are non-invasive, probe-free techniques that have been used extensively in such systems to probe length scales ranging from angstroms to microns, and dynamics occurring over picosecond to millisecond time scales. Recent developments in the area of phase separated lipid systems mimicking membrane rafts will be presented, and the underlying concepts of the different scattering techniques used to study them will be discussed in detail.

Graphical abstract: On scattered waves and lipid domains: detecting membrane rafts with X-rays and neutrons

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Publication details

The article was received on 21 Jul 2015, accepted on 21 Sep 2015 and first published on 21 Sep 2015


Article type: Tutorial Review
DOI: 10.1039/C5SM01807B
Citation: Soft Matter, 2015,11, 9055-9072
  • Open access: Creative Commons BY license
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    On scattered waves and lipid domains: detecting membrane rafts with X-rays and neutrons

    D. Marquardt, F. A. Heberle, J. D. Nickels, G. Pabst and J. Katsaras, Soft Matter, 2015, 11, 9055
    DOI: 10.1039/C5SM01807B

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