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Issue 11, 2015
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PhI(OAc)2-mediated functionalisation of unactivated alkenes for the synthesis of pyrazoline and isoxazoline derivatives

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Abstract

A PhI(OAc)2-promoted radical cyclization of β,γ-unsaturated hydrazones and oximes has been developed for an efficient synthesis of various valuable pyrazoline and isoxazoline derivatives with satisfactory yields (up to 96%) under mild conditions.

Graphical abstract: PhI(OAc)2-mediated functionalisation of unactivated alkenes for the synthesis of pyrazoline and isoxazoline derivatives

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Publication details

The article was received on 07 Jan 2015, accepted on 30 Jan 2015 and first published on 30 Jan 2015


Article type: Paper
DOI: 10.1039/C5OB00029G
Citation: Org. Biomol. Chem., 2015,13, 3457-3461
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    PhI(OAc)2-mediated functionalisation of unactivated alkenes for the synthesis of pyrazoline and isoxazoline derivatives

    X. Hu, G. Feng, J. Chen, D. Yan, Q. Zhao, Q. Wei and W. Xiao, Org. Biomol. Chem., 2015, 13, 3457
    DOI: 10.1039/C5OB00029G

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