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Issue 7, 2015
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Engineering DNA scaffolds for delivery of anticancer therapeutics

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Abstract

Engineering DNA nanostructures with programmability in size, shape and surface chemistry holds tremendous promise in biomedical applications. As an emerging platform for drug delivery, DNA nanostructures have been extensively studied for delivering anticancer therapeutics, including small-molecule drug, nucleic acids and proteins. In this mini-review, current advances in utilizing DNA scaffolds as drug carriers for cancer treatment were summarized and future challenges were also discussed.

Graphical abstract: Engineering DNA scaffolds for delivery of anticancer therapeutics

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Publication details

The article was received on 29 Dec 2014, accepted on 13 Feb 2015 and first published on 25 Feb 2015


Article type: Minireview
DOI: 10.1039/C4BM00459K
Citation: Biomater. Sci., 2015,3, 1018-1024
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    Engineering DNA scaffolds for delivery of anticancer therapeutics

    W. Sun and Z. Gu, Biomater. Sci., 2015, 3, 1018
    DOI: 10.1039/C4BM00459K

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