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Issue 3, 2015
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The synthesis of head-to-tail cyclic sulfono-γ-AApeptides

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Abstract

We report an efficient method for the preparation of unprecedented head-to-tail cyclic sulfono-γ-AApeptides. Following this method, a number of cyclic sequences bearing two to five subunits were efficiently synthesized. In addition, the X-ray crystal structure study of a three-membered cyclic sulfono-γ-AApeptide revealed a type II β-turn-like character.

Graphical abstract: The synthesis of head-to-tail cyclic sulfono-γ-AApeptides

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Publication details

The article was received on 20 Oct 2014, accepted on 18 Nov 2014 and first published on 18 Nov 2014


Article type: Communication
DOI: 10.1039/C4OB02232G
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Citation: Org. Biomol. Chem., 2015,13, 672-676
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    The synthesis of head-to-tail cyclic sulfono-γ-AApeptides

    H. Wu, F. She, W. Gao, A. Prince, Y. Li, L. Wei, A. Mercer, L. Wojtas, S. Ma and J. Cai, Org. Biomol. Chem., 2015, 13, 672
    DOI: 10.1039/C4OB02232G

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