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Issue 13, 2013
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Recent developments in microfluidics-based chemotaxis studies

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Abstract

Microfluidic devices can better control cellular microenvironments compared to conventional cell migration assays. Over the past few years, microfluidics-based chemotaxis studies showed a rapid growth. New strategies were developed to explore cell migration in manipulated chemical gradients. In addition to expanding the use of microfluidic devices for a broader range of cell types, microfluidic devices were used to study cell migration and chemotaxis in complex environments. Furthermore, high-throughput microfluidic chemotaxis devices and integrated microfluidic chemotaxis systems were developed for medical and commercial applications. In this article, we review recent developments in microfluidics-based chemotaxis studies and discuss the new trends in this field observed over the past few years.

Graphical abstract: Recent developments in microfluidics-based chemotaxis studies

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Publication details

The article was received on 04 Apr 2013, accepted on 14 May 2013 and first published on 28 May 2013


Article type: Critical Review
DOI: 10.1039/C3LC50415H
Citation: Lab Chip, 2013,13, 2484-2499
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    Recent developments in microfluidics-based chemotaxis studies

    J. Wu, X. Wu and F. Lin, Lab Chip, 2013, 13, 2484
    DOI: 10.1039/C3LC50415H

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