Issue 88, 2013
From the journal:

Chemical Communications

Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis†

Seol-Hee Kim,‡a   Jong-Ho Kim,‡b   Dong Gil You,c   Gurusamy Saravanakumar,a   Hong Yeol Yoon,c   Ki Young Choi,c   Thavasyappan Thambi,a   V. G. Deepagan,a   Dong-Gyu Jo*d  and  Jae Hyung Park*ae  

* Corresponding authors

a Department of Chemical Engineering, Kyung Hee University, Gyeonggi-do 449-701, Republic of Korea

b Department of Pharmaceutical Science, Kyung Hee University, Seoul 130-701, Republic of Korea

c Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul 130-701, Republic of Korea

d School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea
E-mail: jodg@skku.edu
Fax: +82-31-292-8800
Tel: +82-31-290-7776

e Department of Polymer Science and Engineering, Sungkyunkwan University, Suwon 440-746, Republic of Korea
E-mail: jhpark1@skku.edu
Fax: +82-31-292-8790
Tel: +82-31-290-7288

Abstract

The amphiphilic block copolymer, composed of hydrophilic dextran sulfate as the targeting ligand and hydrophobic polycaprolactone as the hydrophobic segment, was prepared via click chemistry to develop self-assembled nanoparticles for targeting rheumatoid arthritis.

Graphical abstract: Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis

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Article information

DOI
https://doi.org/10.1039/C3CC44260H
Article type
Communication
Submitted
06 Jun 2013
Accepted
19 Jul 2013
First published
22 Jul 2013

Chem. Commun., 2013,49, 10349-10351

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Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis

S. Kim, J. Kim, D. G. You, G. Saravanakumar, H. Y. Yoon, K. Y. Choi, T. Thambi, V. G. Deepagan, D. Jo and J. H. Park, Chem. Commun., 2013, 49, 10349 DOI: 10.1039/C3CC44260H

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