Design of 7-amino-6-chloro-3H-imidazo[4,5-b]pyridine scaffold from 5-chloro-2,4-diaminopyrimidine pharmacophore: identification of potent inhibitors of anaplastic lymphoma kinase†
Abstract
A series of potent anaplastic lymphoma kinase (ALK)
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* Corresponding authors
a
Cephalon, Inc., a wholly-owned, indirect subsidiary of Teva Pharmaceutical Industries Ltd., 145 Brandywine Parkway, West Chester, PA 19380, USA
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A series of potent anaplastic lymphoma kinase (ALK)
K. S. Learn, J. C. Wagner, M. S. Albom, T. S. Angeles, Z. Huang, A. K. Ghose, W. Wan, M. Cheng, B. D. Dorsey and G. R. Ott, Med. Chem. Commun., 2012, 3, 1138 DOI: 10.1039/C2MD20061A
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