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Correction: Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions

George M. Burslem ab, Hannah F. Kyle bc, Adam Nelson ab, Thomas A. Edwards bc and Andrew J. Wilson *ab
aSchool of Chemistry, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, UK. E-mail: a.j.wilson@leeds.ac.uk
bAstbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, UK
cSchool of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, UK

Received 16th May 2017 , Accepted 16th May 2017

First published on 6th June 2017


Abstract

Correction for ‘Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions’ by George M. Burslem et al., Chem. Sci., 2017, DOI: 10.1039/c7sc00388a.


The authors regret that Fig. 3 is incorrect in the original manuscript. The chemical structure of VH298 was shown with an oxazole ring instead of the correct methyl-thiazole ring. The correct figure is displayed below.
image file: c7sc90030a-f3.tif
Fig. 3 Modulators of the HIF pathway (a) topotecan and derivative EZN-2208 (b) 2-oxoglutarate (c) DMOG and oxalyl glycine (d) FG-2216 (e) roxadustat (f) geldanamycin (g) ganetespib (h) X-ray crystal structure of a hydroxyproline derived inhibitor (orange) bound to pVHL (cyan), PDB ID 3zrc (i) optimised hydroxyproline derived pVHL inhibitor VH298 (j) echinomycin (k) DNA sequence specific polyamide (l) bortezomib.

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


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