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Themed collection Lab on a Chip Pioneers of Miniaturization Lectureship winners

12 items
Paper

Biophysical isolation and identification of circulating tumor cells

The integrated vortex enrichment–deformability cytometry device may enable automated enumeration of circulating tumor cells from blood by mechanophenotyping.

Graphical abstract: Biophysical isolation and identification of circulating tumor cells
Paper

A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications

A vascularized, perfused organ-on-a-chip platform suitable for large-scale drug efficacy/toxicity screening.

Graphical abstract: A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications
From the themed collection: Organ-, body- and disease-on-a-chip systems
Paper

An inkjet printed, roll-coated digital microfluidic device for inexpensive, miniaturized diagnostic assays

Inkjet printing is combined with roll-coating to fabricate digital microfluidic (DMF) devices outside of the cleanroom for inexpensive, miniaturized diagnostic assays, with straightforward scalability towards mass production.

Graphical abstract: An inkjet printed, roll-coated digital microfluidic device for inexpensive, miniaturized diagnostic assays
Paper

Bioprinted thrombosis-on-a-chip

A novel bioprinted model of thrombosis was developed to study thrombosis and thrombolysis in vitro.

Graphical abstract: Bioprinted thrombosis-on-a-chip
From the themed collection: Organ-, body- and disease-on-a-chip systems
Paper

Engineering a perfusable 3D human liver platform from iPS cells

The authors present a human liver model that supports both primary hepatocytes and human iHeps with flexibility for systems integration.

Graphical abstract: Engineering a perfusable 3D human liver platform from iPS cells
Paper

Wash-free magnetic immunoassay of the PSA cancer marker using SERS and droplet microfluidics

We report a novel wash-free magnetic immunoassay technique for prostate-specific antigen that uses a surface-enhanced Raman scattering-based microdroplet sensor.

Graphical abstract: Wash-free magnetic immunoassay of the PSA cancer marker using SERS and droplet microfluidics
Paper

Surface-tension driven open microfluidic platform for hanging droplet culture

A hanging droplet culture platform enabling culture of shear-sensitive and suspension cells with a high degree of accessibility to culture.

Graphical abstract: Surface-tension driven open microfluidic platform for hanging droplet culture
Paper

A cost-effective fluorescence mini-microscope for biomedical applications

A miniature microscope was designed and fabricated with built-in fluorescence capability for biomedical applications.

Graphical abstract: A cost-effective fluorescence mini-microscope for biomedical applications
Open Access Paper

Photopatterned oil-reservoir micromodels with tailored wetting properties

We present a new method to fabricate oil-reservoir micromodels with heterogeneous wetting properties.

Graphical abstract: Photopatterned oil-reservoir micromodels with tailored wetting properties
Paper

Whole blood human neutrophil trafficking in a microfluidic model of infection and inflammation

Inflammation on a chip.

Graphical abstract: Whole blood human neutrophil trafficking in a microfluidic model of infection and inflammation
Paper

Microfluidic serial digital to analog pressure converter for arbitrary pressure generation and contamination-free flow control

Microfluidic serial digital to analog pressure converter can generate arbitrary analog pressures on-chip for real time, automated flow control.

Graphical abstract: Microfluidic serial digital to analog pressure converter for arbitrary pressure generation and contamination-free flow control
Paper

Immuno-pillar chip: a new platform for rapid and easy-to-use immunoassay

We present a new rapid and easy-to-use immunoassay chip which we have named the immuno-pillar chip. It has hydrogel pillars, fabricated inside a microchannel, with many antibody molecules immobilized onto 1 µm diameter polystyrene beads.

Graphical abstract: Immuno-pillar chip: a new platform for rapid and easy-to-use immunoassay
From the themed collection: 10th Anniversary Issue: Japan
12 items

About this collection

Collection of papers authored by winners of the Lab on a Chip Pioneers of Miniaturization Lectureship. Nominations open in spring each year and winners are announced in late summer. The winners give a lecture at the annual MicroTAS conference.

For more information on how to nominate for the 2018 Lectureship, please visit the journal blog.

2017 winner: Professor Aaron Wheeler, University of Toronto, Canada

2017 Winner profile: Aaron Wheeler earned his PhD in Chemistry at Stanford University in 2003. After a postdoctoral fellowship at UCLA, he joined the faculty at the University of Toronto in 2005, with primary appointment in the Department of Chemistry and cross-appointments in the Institute for Biomaterials and Biomedical Engineering and the Donnelly Centre for Cellular and Biomolecular Research. Wheeler’s research group develops microfluidic tools to solve problems in chemistry, biology, and medicine. A key technology used by the group is digital microfluidics  (DMF), a technique in which fluidic droplets are manipulated on the surface of an array of electrodes coated with a hydrophobic insulator. In recent years DMF has matured into a highly enabling liquid-handling technology which has a strong foothold in several fields ranging from chemical synthesis to clinical sample analysis to tissue engineering. Learn about the Wheeler group online http://microfluidics.utoronto.ca/ or on twitter at @Wheeler_Lab.

Previous winners:

2016: Professor Daniel Irimia, Massachusetts General Hospital, USA

2015: Professor Dino Di Carlo, University of California, Los Angeles, USA

2014: Professor Sangeeta N. Bhatia, Massachusetts Institute of Technology, USA

2013: Professor Shuichi Takayama, University of Michigan, USA

2012: Professor Andrew deMello, ETH Zürich, Switzerland

2011: Professor Ali Khademhosseini, Massachusetts Institute of Technology, USA

2010: Professor Stephen Quake, Stanford University, USA

2009: Professor Abe Lee, University of California, Irvine, USA

2008: Dr Patrick Doyle, Massachusetts Institute of Technology, USA

2007: Dr Manabu Tokeshi, Nagoya University, Japan

2006: Dr David Beebe, University of Wisconsin, USA

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