Issue 22, 2012

Synthesis of optically active dihydropyrans from asymmetric [4 + 2] cycloaddition of β,γ-unsaturated α-ketoesters with allenic esters

Abstract

β-Isocupreidine (β-ICD) catalyzed asymmetric [4 + 2] cycloaddition of β,γ-unsaturated α-ketoesters with allenic esters afforded ester-substituted functionalized dihydropyran derivatives in high yields along with high enantioselectivities under mild conditions.

Graphical abstract: Synthesis of optically active dihydropyrans from asymmetric [4 + 2] cycloaddition of β,γ-unsaturated α-ketoesters with allenic esters

Supplementary files

Article information

Article type
Paper
Submitted
05 Mar 2012
Accepted
12 Apr 2012
First published
16 Apr 2012

Org. Biomol. Chem., 2012,10, 4355-4361

Synthesis of optically active dihydropyrans from asymmetric [4 + 2] cycloaddition of β,γ-unsaturated α-ketoesters with allenic esters

C. Pei, Y. Jiang and M. Shi, Org. Biomol. Chem., 2012, 10, 4355 DOI: 10.1039/C2OB25475A

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