Barbituric acid as a new locking fragment in macrocyclization: synthesis and structural characterization of [aqua(perchlorato)(2′,4′,6′-trioxohexahydropyrimidine-5′-spiro-6-1,4,8,11- tetraazacyclotetradecane)copper(II)] perchlorate hydrate
Abstract
The reaction of [Cu(danda)]2+(danda = 3,7-diazanonane-1,9-diamine) with formaldehyde and barbituric acid resulted in a new macrocyclic compound, bearing barbituric acid as a spiro substituent which was characterized by spectral and potentiometric methods, cyclic voltammetry and single-crystal X-ray diffraction.