Issue 84, 2013
From the journal:

Chemical Communications

Facile and efficient KOH-catalysed reduction of esters and tertiary amides†

José A. Fernández-Salas,a   Simone Manzinia  and  Steven P. Nolan*a  

* Corresponding authors

a EaStCHEM School of Chemistry, University of St Andrews, St Andrews, KY16 9ST, UK
E-mail: snolan@st-andrews.ac.uk

Abstract

Esters and tertiary amides were efficiently reduced to their corresponding alcohols and amines in high yields under mild and environmentally friendly conditions. The presented KOH-catalysed system involves a simple hydrosilylation procedure that is carried out under solvent-free conditions and does not require the use of inert conditions.

Graphical abstract: Facile and efficient KOH-catalysed reduction of esters and tertiary amides

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Article information

DOI
https://doi.org/10.1039/C3CC45930F
Article type
Communication
Submitted
02 Aug 2013
Accepted
28 Aug 2013
First published
03 Sep 2013

Chem. Commun., 2013,49, 9758-9760

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Facile and efficient KOH-catalysed reduction of esters and tertiary amides

J. A. Fernández-Salas, S. Manzini and S. P. Nolan, Chem. Commun., 2013, 49, 9758 DOI: 10.1039/C3CC45930F

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