Issue 5, 2011
From the journal:

Chemical Communications

Synthesis of covalently linked parallel and antiparallel DNA duplexes containing the metal-mediated base pairs T–Hg(ii)–T and C–Ag(i)–C†

Takashi Ono,a   Kyohei Yoshida,a   Yuko Saotome,a   Rei Sakabe,a   Itaru Okamotoa  and  Akira Ono*a  

* Corresponding authors

a Department of Material & Life Chemistry, Faculty of Engineering, Kanagawa University, 3-27-1 Rokkakubashi, Kanagawa-ku, Yokohama, Kanagawa 221-8686, Japan
E-mail: akiraono@kanagawa-u.ac.jp
Fax: +81 454917915
Tel: +81 454815661

Abstract

DNA duplexes fixed in anti-parallel and parallel orientations by introducing covalent linkages have been synthesized and metal ions, Hg(II) and Ag(I), were incorporated into pyrimidine–pyrimidine base pairs.

Graphical abstract: Synthesis of covalently linked parallel and antiparallel DNA duplexes containing the metal-mediated base pairs T–Hg(ii)–T and C–Ag(i)–C

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Article information

DOI
https://doi.org/10.1039/C0CC02028A
Article type
Communication
Submitted
23 Jun 2010
Accepted
04 Nov 2010
First published
22 Nov 2010

Chem. Commun., 2011,47, 1542-1544

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Synthesis of covalently linked parallel and antiparallel DNA duplexes containing the metal-mediated base pairs T–Hg(II)–T and C–Ag(I)–C

T. Ono, K. Yoshida, Y. Saotome, R. Sakabe, I. Okamoto and A. Ono, Chem. Commun., 2011, 47, 1542 DOI: 10.1039/C0CC02028A

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