Issue 5, 2011
From the journal:

Chemical Communications

Dual MRI-SPECT agent for pH-mapping†

Eliana Gianolio,a   Luca Maciocco,b   Daniela Imperio,c   Giovanni B. Giovenzana,c   Federica Simonelli,d   Kamel Abbas,d   Gianni Bisie  and  Silvio Aime*a  

* Corresponding authors

a Department of Chemistry IFM and Molecular Imaging Center, University of Torino, Via Nizza 52, Torino, Italy
E-mail: silvio.aime@unito.it
Fax: +390116706487
Tel: +390116706451

b Advanced Accelerator Applications (AAA), St. Genis Pouilly, France

c DiSCAFF, Università del Piemonte Orientale “A. Avogadro”, Via Bovio 6, 28100 Novara, Italy

d Institute for Health and Consumer Protection Joint Research Centre, European Commission Cyclotron, Via Fermi, 2749 I-21020 Ispra (VA), Italy

e University of Torino, Nucl Med Serv, Azienda Osped San Giovanni Battista, Dipartimento Med Interna Corso Bramante 88, I-10126 Torino, Italy

Abstract

A new dual MRI/SPECT pH-responsive agent where the SPECT active moiety acts as reporter of the concentration making it possible to exploit the responsiveness of the MRI probe.

Graphical abstract: Dual MRI-SPECT agent for pH-mapping

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Article information

DOI
https://doi.org/10.1039/C0CC03554H
Article type
Communication
Submitted
30 Aug 2010
Accepted
03 Nov 2010
First published
19 Nov 2010

Chem. Commun., 2011,47, 1539-1541

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Dual MRI-SPECT agent for pH-mapping

E. Gianolio, L. Maciocco, D. Imperio, G. B. Giovenzana, F. Simonelli, K. Abbas, G. Bisi and S. Aime, Chem. Commun., 2011, 47, 1539 DOI: 10.1039/C0CC03554H

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