Issue 20, 1988

Complete stereoselective synthesis of chiral intermediates for thienamycin and related antibiotics

Abstract

The complete stereoselective synthesis of (3R,4R)-3-[(S)-1′-hydroxyethyl]-4-phenylethynyl-2-azetidinone and its 4-phenyethenyl derivative were accomplished by the reaction of the organozinc derivative of (R)-methyl-3-hydroxybutyrate with N-trimethylsilylimines.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1988, 1376-1377

Complete stereoselective synthesis of chiral intermediates for thienamycin and related antibiotics

N. Oguni and Y. Ohkawa, J. Chem. Soc., Chem. Commun., 1988, 1376 DOI: 10.1039/C39880001376

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