Issue 2, 2008
From the journal:

Analyst

Quantitative analysis by microchip capillary electrophoresis – current limitations and problem-solving strategies

Tobias Revermann,ab   Sebastian Götz,a   Jens Künnemeyerb  and  Uwe Karst*ab  

* Corresponding authors

a Chemical Analysis Group and MESA+ Institute for Nanotechnology, University of Twente, Enschede, The Netherlands

b Institut für Anorganische und Analytische Chemie, Westfälische Wilhelms-Universität Münster, Corrensstraße 30, 48149 Münster, Germany
E-mail: uk@uni-muenster.de
Fax: +49-251-8336013
Tel: +49-251-8333141

Abstract

Obstacles and possible solutions for the application of microchip capillary electrophoresis in quantitative analysis are described and critically discussed. Differences between the phenomena occurring during conventional capillary electrophoresis and microchip-based capillary electrophoresis are pointed out, with particular focus on electrolysis, bubble formation, clogging, surface interactions, injection and aspects related to the power supply. Current drawbacks are specified and improvements for successful quantitative microchip capillary electrophoresis are suggested.

Graphical abstract: Quantitative analysis by microchip capillary electrophoresis – current limitations and problem-solving strategies

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Article information

DOI
https://doi.org/10.1039/B711165G
Article type
Tutorial Review
First published
02 Nov 2007

Analyst, 2008,133, 167-174

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Quantitative analysis by microchip capillary electrophoresis – current limitations and problem-solving strategies

T. Revermann, S. Götz, J. Künnemeyer and U. Karst, Analyst, 2008, 133, 167 DOI: 10.1039/B711165G

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