Issue 2, 2008
From the journal:

Analyst

Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry

Matthew J. Baker,*a   Michael D. Brown,b   Ehsan Gazi,b   Noel W. Clarke,bcd   John C. Vickermana  and  Nicholas P. Lockyera  

* Corresponding authors

a Manchester Interdisciplinary Biocentre, Centre for Instrumentation and Analytical Science, School of Chemical Engineering and Analytical Science, The University of Manchester, UK
E-mail: M.Baker-2@postgrad.manchester.ac.uk

b ProMPT Genito Urinary Cancer Research Group, Paterson Institute for Cancer Research, The University of Manchester, Christie Hospital NHS Foundation Trust, Manchester, UK

c Department of Urology, Christie Hospital NHS Foundation Trust, Manchester, UK

d Department of Urology, Salford Royal NHS Foundation Trust, Salford, UK

Abstract

This communication utilises Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) combined with multivariate analysis to obtain spectra from the surfaces of three closely related cell lines allowing their discrimination based upon mass spectral ions.

Graphical abstract: Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry

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Article information

DOI
https://doi.org/10.1039/B712853C
Article type
Communication
Submitted
21 Aug 2007
Accepted
21 Nov 2007
First published
30 Nov 2007

Analyst, 2008,133, 175-179

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Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry

M. J. Baker, M. D. Brown, E. Gazi, N. W. Clarke, J. C. Vickerman and N. P. Lockyer, Analyst, 2008, 133, 175 DOI: 10.1039/B712853C

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