Jump to main content
Jump to site search


Hydroxy-assisted regio- and stereoselective synthesis of functionalized alkenes via phosphine-catalyzed β′-umpolung addition of o-hydroxy aromatic aldimines to allenoates

Author affiliations

Abstract

An unprecedented β′-umpolung addition of o-hydroxy aromatic aldimines with allenoates has been developed under the catalysis of phosphine. The reaction provides an efficient approach to the synthesis of functionalized alkenes in moderate to good yields with high stereoselectivities under mild conditions. The asymmetric version of this β′-umpolung addition has also been studied using chiral phosphines.

Graphical abstract: Hydroxy-assisted regio- and stereoselective synthesis of functionalized alkenes via phosphine-catalyzed β′-umpolung addition of o-hydroxy aromatic aldimines to allenoates

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 May 2018, accepted on 28 Jun 2018 and first published on 28 Jun 2018


Article type: Research Article
DOI: 10.1039/C8QO00460A
Citation: Org. Chem. Front., 2018, Advance Article
  •   Request permissions

    Hydroxy-assisted regio- and stereoselective synthesis of functionalized alkenes via phosphine-catalyzed β′-umpolung addition of o-hydroxy aromatic aldimines to allenoates

    K. Cheng, Y. Bao, J. Wang, Z. Dai, J. Lu and Q. Zhou, Org. Chem. Front., 2018, Advance Article , DOI: 10.1039/C8QO00460A

Search articles by author

Spotlight

Advertisements