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Issue 13, 2018
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Visible light-induced aerobic oxidative cross-coupling of glycine derivatives with indoles: a facile access to 3,3′ bisindolylmethanes

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Abstract

A visible light-induced aerobic oxidative cross-coupling of glycine derivatives with indoles has been developed to efficiently synthesize 3,3′-bisindolylmethanes (BIMs). The reaction proceeds smoothly under mild conditions and exhibits good tolerance of functional groups. The applicability of this method was highlighted in the expedient total syntheses of the alkaloid natural products streptindole and arsindoline B in two steps, respectively.

Graphical abstract: Visible light-induced aerobic oxidative cross-coupling of glycine derivatives with indoles: a facile access to 3,3′ bisindolylmethanes

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Publication details

The article was received on 04 Apr 2018, accepted on 26 May 2018 and first published on 29 May 2018


Article type: Research Article
DOI: 10.1039/C8QO00341F
Citation: Org. Chem. Front., 2018,5, 2120-2125
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    Visible light-induced aerobic oxidative cross-coupling of glycine derivatives with indoles: a facile access to 3,3′ bisindolylmethanes

    Y. Zhang, X. Yang, H. Zhou, S. Li, Y. Zhu and Y. Li, Org. Chem. Front., 2018, 5, 2120
    DOI: 10.1039/C8QO00341F

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