Jump to main content
Jump to site search

Issue 37, 2016
Previous Article Next Article

Total synthesis of mangiferin, homomangiferin, and neomangiferin

Author affiliations

Abstract

Total synthesis of mangiferin, homomangiferin, and neomangiferin, three C-glycosyl xanthone natural products with a wide spectrum of pharmacological effects, has been achieved starting from 2,3,4,6-tetra-O-benzyl-α/β-D-glucopyranose. The key steps involve a stereoselective Lewis acid promoted C-glycosylation of protected phloroglucinol with tetrabenzylglucopyranosyl acetate and a highly regioselective base-induced cyclization for the construction of the core xanthone skeleton.

Graphical abstract: Total synthesis of mangiferin, homomangiferin, and neomangiferin

Back to tab navigation

Supplementary files

Publication details

The article was received on 29 Jul 2016, accepted on 22 Aug 2016 and first published on 22 Aug 2016


Article type: Paper
DOI: 10.1039/C6OB01622G
Citation: Org. Biomol. Chem., 2016,14, 8821-8831
  •   Request permissions

    Total synthesis of mangiferin, homomangiferin, and neomangiferin

    X. Wei, D. Liang, Q. Wang, X. Meng and Z. Li, Org. Biomol. Chem., 2016, 14, 8821
    DOI: 10.1039/C6OB01622G

Search articles by author

Spotlight

Advertisements