Jump to main content
Jump to site search

Issue 5, 2016
Previous Article Next Article

Gold nanoparticles as sensitive optical probes

Author affiliations

Abstract

Gold nanoparticles (Au NPs) have become one of the most popular materials for sensing of analytes of interest in the last decade, mainly because of their ease in preparation and conjugation, stability, biocompatibility, and size-dependent optical properties. We have witnessed many sensitive and selective Au NP based optical systems for the quantitation of metal ions, anions, proteins, and DNA, based on analyte induced changes in their absorption, fluorescence, and scattering. In this tutorial review, we briefly discuss wet chemical approaches for the preparation of Au NPs. Sensing mechanisms and strategies of Au NP based optical systems are provided to show basic concepts in designing sensitive and selective sensing systems. Strategies for signal amplification applied in Au NP based systems are emphasized for the analysis of trace amounts of analytes in real samples. Many excellent Au NP based optical sensing systems are discussed to highlight their practicality for the analysis of complicated biological and environmental samples. The tutorial review ends with the discussion of the challenges and future trends of Au NP based optical sensing systems.

Graphical abstract: Gold nanoparticles as sensitive optical probes

Back to tab navigation

Publication details

The article was received on 28 Dec 2015, accepted on 26 Jan 2016 and first published on 26 Jan 2016


Article type: Tutorial Review
DOI: 10.1039/C5AN02651B
Citation: Analyst, 2016,141, 1611-1626
  • Open access: Creative Commons BY license
  •   Request permissions

    Gold nanoparticles as sensitive optical probes

    Z. Yuan, C. Hu, H. Chang and C. Lu, Analyst, 2016, 141, 1611
    DOI: 10.1039/C5AN02651B

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements